Structure-Activity Relationships in Cannabinoids

[Rhodium]

Structure-Activity Relationships in Cannabinoids
Raj K. Razdan

Pharmacological Reviews Vol. 38, No. 2, 75-149 (1986)

(https://www.thevespiary.org/rhodium/Rhodium/djvu/cannabinoid-sar.djvu)

I. Introduction
II. Drug development: an overview
III. Assessment of biological activity
https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif" title="View this image">A. Dog ataxia test
https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif" title="View this image">B. Monkey behavioral test
https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif" title="View this image">C. Mouse ring immobility assay
https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif" title="View this image">D. Tetrahydrocannabinol-seizure susceptible (THC-SS) rabbit model
https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif" title="View this image">E. Spontaneous activity and body temperature in mice
https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif" title="View this image">F. Drug discrimination procedure
https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif" title="View this image">G. Conclusions
IV. Structure-activity relationships (SAR)
https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif" title="View this image">A. SAR in man
https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif" title="View this image">B. SAR in animals
V. Conclusion